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| Catalog Number | C-400 |
| Product Name | 5-(and-6)-carboxy-2',7'-dichlorodihydrofluorescein diacetate (carboxy-H2DCFDA) *mixed isomers* |
| Unit Size | 25 mg |
| Description | Carboxy-H2DCFDA is a cell-permeant indicator for reactive oxygen species that is nonfluorescent until the acetate groups are removed by intracellular esterases and oxidation occurs within the cell. The dye has two negative charges at physiological pH, allowing for better retention by cells as compared to the H2DCFDA (D-399). |
| Handbook Section(s) | 10.5 Substrates for Oxidases, Including Amplex Red Kits  |
| 15.2 Viability and Cytotoxicity Assay Reagents | |
| 19.2 Generating and Detecting Reactive Oxygen Species | |
| Product Information Sheet(s) | Acetoxymethyl (AM) and Acetate Esters |
| Bibliography | Bibliography for C-400 |
| Structure | Structure for C-400 |
| MSDS | Material Safety Data Sheet |
| More Information | http://www.probes.com/servlets/product?item=400 |
