products | A.G. Scientific

A.G. Scientific, Inc.

A.G. Scientific is dedicated to supplying the most ínnovative tools to accelerate your scientific research. The product lines include: Angiogenesis, Antibiotics, Apoptosis, Calcium Metaboslism, Cancer Research, Caspases, Cell Culture, Enzyme Activators & Inhibitors, Inositol Phosphatases, Immunsuppression, Ionophors, Neurochemicals, Nitric Oxide/Oxidative Stress, Oligonucleotides, Plant hormones, Proteasomes, Protein Kinases and Signal Transduction.

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Below you will find some selected A.G. Scientific products.

Antibiotics

Hygromycin B, Streptomyces hygroscopicus, Concentrated Solution

Description: An aminoglycosidic antibiotic. Used for the selection and maintenance of pro- and eukaryotic cells transfected with the E. coli hygromycin resistance gene.The working concentration for mammalian cell selection is normally between 50 ug/ml and 1mg/ml, Plant cells: 20-200 ug/ml, Bacteria: 20-200 ug/ml and Fungi: 200 ug-1mg/ml. Your appropriate concentration should be tested experimentally.
Chemical Formula: C_²0H₃₇N₃O₁₃
Chemical Name: O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-O-beta-D-talopyranosyl(1-5)-2-deoxy-N3-methyl-D-streptamine
Molecular Weight: 527.53
Solubility: Soluble in Water
CAS Number: CAS [31282-04-9]

G-418 Geneticin

Description: Aminoglycoside used as a selective agent of transfected mammalian, yeast, plant and bacteria cells. Resistance is conferred by the bacterial gene for aminoglycoside-3'-phophotransferase that can be expressed in eukaryotic cells. Related to Gentamycin.
Chemical Formula: C₂₀H₄₀O₁₀N₄ x 2 H₂SO₄
Molecular Weight: 692.7
Solubility: Soluble in Water and Aqueous Buffers
CAS Number: CAS [108321-42-2] RTECS: CB9378500

Puromycin

Description: Antibiotic used for selecting mammalian cell lines, which have been transformed by vectors that express puromycin-N-acetyl-transferase.
Chemical Formula: C₂₂H₂₉N₇O₅ x 2 HCl
Chemical Name: (S) 3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine,3'-(a-Amino-p-methoxy-hydocinnamamido)-3'-deoxy-N,N-dimethyladenosine x 2HCl
Molecular Weight: 544.5
Solubility: Soluble in Water (50mg/ml)
CAS Number: CAS [58-58-2]

Cycloheximide, Streptomyces griseus

Description: Antibiotic which acts as an inhibitor of protein synthesis in eukaryotes but not prokaryotes. Used primarily in the selection wild type CAN1, CYH2 and LYS2 genes.
Chemical Formula: C₁₅H₂₃NO₄
Molecular Weight: 281.3
Solubility: Soluble in Chloroform, Ethanol and Methanol
CAS Number: CAS [66-81-9]

Mycophenolic Acid, MPA

Description: Antibiotic useful for selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase). Also immunosuppressive agent.
Chemical Formula: C₁₇H₂₀O₆
Chemical Name: 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Molecular Weight: 320.3
Solubility: Soluble in Methane and Methylene Chloride
CAS Number: CAS [24280-93-1]

Gentamycin Sulfate, USP Grade

Description: Broad spectrum, cell culture antibiotic that is non toxic to viruses and mammalian cells at antibacterial levels. It is useful for long-term virus and tissue culture studies. Inhibits protein synthesis by binding to L6 protein of 50S ribosomal subunit.
Solubility: Soluble in Water and DMF
CAS Number: CAS [1405-41-0]

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